BACKGROUND: Metastatic melanoma has shown only limited responsiveness to chemotherapy or immunotherapy.The most commonly used single-agent chemotherapy comes from the nitrosourea group of agents and provides response rates of less than 20%.Several cytotoxic agents have been combined with no dramatic benefit.The incorporation of tamoxifen or interfe
Genotype II African swine fever virus (ASFV) has been plaguing Asian pig industry since 2018.Recently, genotype I ASFV was reported for the first time in China.Since there is no commercial vaccine available against ASFV, early onsite detection and quick culling procedures are commonly used by many countries all over the world.It is important that t
Hereditary deafness is one of the most common human birth defects.GJB2 gene mutation is the most genetic etiology.Gap junction protein 26 (connexin26, Cx26) encoded by the GJB2 gene, which is Coffee Grinder responsible for intercellular substance transfer and signal communication, plays a critical role in hearing acquisition and maintenance.The aud
A uniform unidirectional nanostructure composed of aluminum tin oxide and ultraviolet (UV)-curable polymer is introduced herein.The nanostructure was produced by UV-nanoimprint lithography (UV-NIL), and the fabricated hybrid film was used as a uniform liquid crystal (LC) alignment SPEARMINT GUM layer.Atomic force microscopy and line profile analysi